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Chapter 1 Introduction to Stem Cell Biology **Õ ¸Éϸ°ûÉúÎïѧ¸ÅÊö
1 Stem Cell Research Timeline--Highlights
1.1 Stem Cell Research History
1.2 The Turning Point in Stem Cell Therapy
2 Introduction of Regenerative Medicine and Stem Cells
3 Types and Origin of Stem Cell
3.1 Stem Cell Classification Based on Differentiation Potential
3.2 Stem Cell Classification Based on Origin
4 Stem Cells and Their Niches
5 Application of Stem Cells
5.1 Stem Cells Used in Regenerative Medicine
5.2 Stem Cells for Drug Screening and Development in Laboratory
5.3 A Muhidisciplinary Field
6 Challenges and Requirements
Supplement
References
Chapter 2 Isolation and Identification of Stem Cells µÚ¶þÕ ¸Éϸ°ûµÄ·ÖÀëÓë¼ø¶¨
1 Embryonic Stem Cells
1.1 Genetic Modification Approaches and Potential Applications
1.2 Methods for Genetic Manipulation
2 Mesenchymal Stem Cells
2.1 Mesenchymal Stem Cells Derived from Human Adipose Tissue
2.2 Mesenchymal Stem Cells from Human Bone Marrow
3 Induced Pluripotent Stem Cells
3.1 Integrating Vectors
3.2 Non-DNA Reprogramming
4 Aduit Neural Stem Ceils
4.1 Neural Stem Cells£ºOrigins and Functions
4.2 AduIt Brains Can Generate New Neurons
4.3 AduIt Neural Stem Cells£ºImplications for Therapy
5 Experimental Method
5.1 Materials
5.2 Methods
Supplement
References
Chapter 3 Stem Cells and Human Diseases µÚÈýÕ ¸Éϸ°ûÓëÈËÀ༲²¡
1 Stem Cell Therapy for Neurological Disorders
1.1 Neural Stem Cells
1.2 Hematopoietic Stem Cells
1.3 Mesenchymal Stem Cells
2 Stem Cell Therapy in Heart Diseases
2.1 Stem Cell¡ªBased Therapies
2.2 Brief Summary
3 Stem Cell Therapy in Diabetes Mellitus
3.1 B-Cell Replacement
3.2 Embryonic Stem Cells
3.3 Induced Pluripotent Stem Cells
3.4 Mesenchymal Stem Cells
3.5 Brief Summary
4 Stem Cell Therapy in Osteoarthritis
4.1 Stem Cell Therapy
4.2 Route of Administration
5 Stem Cell Therapy in Wound Healing
5.1 Stages of Wound
5.2 Chronic Wounds
5.3 Types of Stem Cells
5.4 Brief Summary
Supplement
References
Chapter 4 Stem Cell£¯Stem Cell Niche and Tissue Regeneration µÚËÄÕ ¸Éϸ°û£¯¸Éϸ°û΢»·¾³Óë×éÖ¯ÔÙÉú
1 Introduction to Stem Cell Niche
1.1 Definition
1.2 Components of the Niche
1.3 Niche Factors
1.4 Recap
2 Introduction to Tissue Engineering for Regeneration Medicine
2.1 Manipulating of the Niche for Regenerative
2.2 The Design of Stem Cell Niche
2.3 Synthetic Niches in Vivo
2.4 Ligand Immobilization
2.5 Tissue Engineering
2.6 Scaffold
2.7 Question
Supplement
Rerefences
Chapter 5 Cancer Stem Cells µÚÎåÕ Ö×Áö¸Éϸ°û
1 Introduction to Cancer Stem Cells
1.1 Definition
1.2 Characteristics
1.3 Mechanism of Cancer Stem Cell Resistance to Therapy
1.4 Origin of Cancer Stem Cells
1.5 Characterize Cancer Stem Cells
1.6 Cancer Stem Cells Markers
1.7 Isolation of Cancer Stem Cells
1.8 The Correlation Between Cancer Stem Cells.Epithelial-Mesenchymal Transition and Vasculogenic Mimicy Formation
2 The Cancer Stem Cell Niche
2.1 Niche Components
2.2 Niche Fartots
2.3 Cancer Stem CeUs Derived from Mouse Induced Pluripotent Stem Cells When Exposed to a Malignant Niche
2.4 Importance of Cancer Stem Cell Niche
3 Challenges and Approaches in Cancer Stem Ceils Research
3.1 Challenges
3.2 Approaches in Cancer Stem Cells Research
Supplement
References
Chapter 6 Organoids µÚÁùÕ ÀàÆ÷¹Ù
1 Introduction to Organoids
1.1 Definition
1.2 Development of Organoids
1.3 Origin of Organoids
1.4 The Culture of Organoids
1.5 The Composition of Organoids
1.6 Identification of Organoids
1.7 The Comparison of Organoids wit